Advantages and disadvantages of automated hematology analyzer.

Coulter Principle
Coulter principle that : the particles suspended in the electrolyte with the electrolytic solution through the orifice tube,the constant current circuit design leads to holes between the inner and outer tubes an instantaneous change in the resistance between two electrodes,a potential pulse.Size and number and size of the particle is proportional to the number of pulse signals.This is mainly based on the blood cells compared to diluent,poor blood cells are made by the characteristics of the conductor.Initially,only the original calculation and measurement Coulter counter erythrocytes.Later,with the continuous improvement of technology continues to evolve and devices,clinicians can also use it to calculate and measure the white blood cells.To the 1970s,the further development of technology allows technicians to separate platelets.
Evolution of automated cell counters
Cytometer in the traditional sense is by studying the peripheral blood smear,using blood cells and white blood cell count and instrument done manually(also known as 100 smear classification,manual leukocyte count or manual counters).According to Kurt principle led to the invention of the Coulter counter,and subsequently developed a technologically advanced automated hemotology analyzer.Since then,the instrument's technical level has been rising.Due to advances in technology,a single instrument can be analyzed more parameters,thus greatly improving the efficiency of the blood test,the reduction of a multiple sample analysis instrument case.Modern cell analyzer capable of measuring white blood cell (wbc),leukocyte(five categories),red blood cells (rbc),hemoglobin (hgb),platelets (plt),mean corpuscular volume (mcv),mean platelet volume,and can automatically calculate blood cells hematocrit (hct),mean corpuscular hemoglobin (mch),mean corpuscular hemoglobin concentration (mchc),red blood cell distribution width,platelet volume and platelet distribution width.
Other important factors include automatic blood analyzer speed and they run the number of samples that can be processed per batch (large processing capacity can reduce the turnaround time).
Instant test (poct)
Instant test (poct) is becoming an important adjunct to the blood lab practice.WBC count can be a blood cell analyzer has been in the intensive care unit and other areas have been practical use.
Contrast manual cell counting and automatic cell count
Although the peripheral blood smear examination of the information provided is automatic cell count can not be obtained,but it still has some limitations and some special requirements.
Manual cell count limitations
Need to have some experience in order to make smears technically maintain adequate standardization and consistency in the operation.
-Is subjective,labor-intensive and statistically unreliable(calculated only 100-200 cells).
-Coefficient of variation reported (cv) from 30% to 110 %,and is inaccurate.
-Counting the cells manually recognition error : This is generally lymphocytes and monocytes want with cell division and abnormal forms of variation(lymphocytes and blasts) separate.Monocytes are often underestimated,and lymphocytes are often overestimated. 

Advantage of the automatic analyzer

Using an automatic biochemistry analyzer for sale cell count is a fast,objective,statistically significant(calculated above 8000 cells),and will not be counted manually due to various biases affected.Compared with manual methods,automated analyzer more efficient,more cost-effective.Some automatic analyzer can handle 120-150 samples per hour.Further,to ensure accurate automatic classification of white blood cell count absolute reliability and reproducibility. 

Inadequacies automatic analyzer

Automatic blood cell analyzer may also cause cell count too much or too little of the phenomenon.Some analyzers especially impedance type counter only checks the size and number of particles,may not correctly distinguish tiny platelet aggregation and nucleated red blood cells.Platelet aggregation may be incorrectly classified as white blood cells or red blood cells,and nucleated red blood cells may also be wrongly classified as white blood cells,lymphocytes are classified as particularly vulnerable.In addition,large or illegible atypical cells,immature neutrophils and toxic reactive lymphocytes are also likely to be incorrectly classified.
The article comes from:http://www.medicalequipment-msl.com/htm/medical-device-book/Advantages-and-disadvantages-of-automated-hematology-analyzer..html

Advantages and disadvantages of automated hematology analyzer.

Coulter Principle
Coulter principle that : the particles suspended in the electrolyte with the electrolytic solution through the orifice tube,the constant current circuit design leads to holes between the inner and outer tubes an instantaneous change in the resistance between two electrodes,a potential pulse.Size and number and size of the particle is proportional to the number of pulse signals.This is mainly based on the blood cells compared to diluent,poor blood cells are made by the characteristics of the conductor.Initially,only the original calculation and measurement Coulter counter erythrocytes.Later,with the continuous improvement of technology continues to evolve and devices,clinicians can also use it to calculate and measure the white blood cells.To the 1970s,the further development of technology allows technicians to separate platelets.
Evolution of automated cell counters
Cytometer in the traditional sense is by studying the peripheral blood smear,using blood cells and white blood cell count and instrument done manually(also known as 100 smear classification,manual leukocyte count or manual counters).According to Kurt principle led to the invention of the Coulter counter,and subsequently developed a technologically advanced automated hemotology analyzer.Since then,the instrument's technical level has been rising.Due to advances in technology,a single instrument can be analyzed more parameters,thus greatly improving the efficiency of the blood test,the reduction of a multiple sample analysis instrument case.Modern cell analyzer capable of measuring white blood cell (wbc),leukocyte(five categories),red blood cells (rbc),hemoglobin (hgb),platelets (plt),mean corpuscular volume (mcv),mean platelet volume,and can automatically calculate blood cells hematocrit (hct),mean corpuscular hemoglobin (mch),mean corpuscular hemoglobin concentration (mchc),red blood cell distribution width,platelet volume and platelet distribution width.
Other important factors include automatic blood analyzer speed and they run the number of samples that can be processed per batch (large processing capacity can reduce the turnaround time).
Instant test (poct)
Instant test (poct) is becoming an important adjunct to the blood lab practice.WBC count can be a blood cell analyzer has been in the intensive care unit and other areas have been practical use.
Contrast manual cell counting and automatic cell count
Although the peripheral blood smear examination of the information provided is automatic cell count can not be obtained,but it still has some limitations and some special requirements.
Manual cell count limitations
Need to have some experience in order to make smears technically maintain adequate standardization and consistency in the operation.
-Is subjective,labor-intensive and statistically unreliable(calculated only 100-200 cells).
-Coefficient of variation reported (cv) from 30% to 110 %,and is inaccurate.
-Counting the cells manually recognition error : This is generally lymphocytes and monocytes want with cell division and abnormal forms of variation(lymphocytes and blasts) separate.Monocytes are often underestimated,and lymphocytes are often overestimated. 

Advantage of the automatic analyzer

Using an automatic biochemistry analyzer for sale cell count is a fast,objective,statistically significant(calculated above 8000 cells),and will not be counted manually due to various biases affected.Compared with manual methods,automated analyzer more efficient,more cost-effective.Some automatic analyzer can handle 120-150 samples per hour.Further,to ensure accurate automatic classification of white blood cell count absolute reliability and reproducibility. 

Inadequacies automatic analyzer

Automatic blood cell analyzer may also cause cell count too much or too little of the phenomenon.Some analyzers especially impedance type counter only checks the size and number of particles,may not correctly distinguish tiny platelet aggregation and nucleated red blood cells.Platelet aggregation may be incorrectly classified as white blood cells or red blood cells,and nucleated red blood cells may also be wrongly classified as white blood cells,lymphocytes are classified as particularly vulnerable.In addition,large or illegible atypical cells,immature neutrophils and toxic reactive lymphocytes are also likely to be incorrectly classified.
The article comes from:http://www.medicalequipment-msl.com/htm/medical-device-book/Advantages-and-disadvantages-of-automated-hematology-analyzer..html

Medical Devices is expected to introduce new regulations to cover a wider range.

It is understood that the medical device industry Cattle Ultrasound Scanner is brewing on a larger scale decree "replacement"recently,according to an official of Jiangsu Food and Drug Administration revealed that at present there are 30 or so levels of regulatory Decree which developed in the study is expected in the near two years of intensive introduction.

"To introduce legislation involving all aspects of the medical device lifecycle,and corporate marketing systems on the market so there will be a very big impact,the impact is expected to be reflected in the next two years."Officials said.
He revealed that the forthcoming legislation will be fully covered by medical device R & D,production,distribution,use of links,including research and development sectors,including the introduction of high-risk medical devices catalog,additional clinical review process,approved medical device clinical trials organization,particularly the trial of innovative medical devices assessment procedures;production processes,including GMP certification;circulation,including Internet sales,third-party logistics and quality management standards,etc.;use of links,including the development of yellow blacklist,launched a comprehensive electronic monitoring,adverse event monitoring and product recalls.
And drug regulation is different,the domestic regulation of medical devices sterilizers for sale is not in place is widespread,management compartmentalization rough,regulatory information,and are not networked,making it difficult for the quality,price and other strict supervision.Since last year,the state passed a provincial organization focused on high- value consumables and other ways to gradually start bidding on the price of medical supplies,the use of more stringent regulation.
The article comes from:http://www.medicalequipment-msl.com/htm/medical-device-news/Medical-Devices-is-expected-to-introduce-new-regulations.html

Medical Devices is expected to introduce new regulations to cover a wider range.

It is understood that the medical device industry Cattle Ultrasound Scanner is brewing on a larger scale decree "replacement"recently,according to an official of Jiangsu Food and Drug Administration revealed that at present there are 30 or so levels of regulatory Decree which developed in the study is expected in the near two years of intensive introduction.

"To introduce legislation involving all aspects of the medical device lifecycle,and corporate marketing systems on the market so there will be a very big impact,the impact is expected to be reflected in the next two years."Officials said.
He revealed that the forthcoming legislation will be fully covered by medical device R & D,production,distribution,use of links,including research and development sectors,including the introduction of high-risk medical devices catalog,additional clinical review process,approved medical device clinical trials organization,particularly the trial of innovative medical devices assessment procedures;production processes,including GMP certification;circulation,including Internet sales,third-party logistics and quality management standards,etc.;use of links,including the development of yellow blacklist,launched a comprehensive electronic monitoring,adverse event monitoring and product recalls.
And drug regulation is different,the domestic regulation of medical devices sterilizers for sale is not in place is widespread,management compartmentalization rough,regulatory information,and are not networked,making it difficult for the quality,price and other strict supervision.Since last year,the state passed a provincial organization focused on high- value consumables and other ways to gradually start bidding on the price of medical supplies,the use of more stringent regulation.
The article comes from:http://www.medicalequipment-msl.com/htm/medical-device-news/Medical-Devices-is-expected-to-introduce-new-regulations.html

India is about to approve the important medical legislation.

According to Indo Asian News Service (Indo Asian News Service) reported that in advance of a regulatory scheme,the Indian Ministry of Health agreed to examine new proposals put forward amendments to the Standing Committee.The Commission's proposal was shelved in December 2013,but now again been studied considering India's coalition cabinet. 
2013 proposed Drug and Cosmetic Act to amend laws governing medical devices do change.Under existing law(passed in 2007),medical devices and equipment are regarded as medicines blood analyzer.The new bill will separate standards and regulations for medical devices out,covering everything from clinical trials to the import and export of all matters.If you want the new regulations approved,coalition cabinet (including the Prime Minister and the Joint Ministerial) must first pass the bill,and get the council to make the final vote. 
Legal change is a big event in India's medical device industry,like Medtronic and Boston Scientific have targeted companies such as emerging markets,while the modern law will also promote long-term investment and major international partnerships. 
Ralph Ives,executive vice president of AdvaMed(Advanced Medical Technology Association of America )Global Strategy Analytics,said: "In the regulatory structure,the medical device is separated from the practice of pharmaceutical products out,indicating that demand for the medical device industry has been recognized by government departments,industries welcome this change and we believe that the face of India's growing health needs,the medical device industry Cheap EKG Machines will provide safe,effective,timely service,and the revised bill will enhance this service capabilities." 
The article comes from:http://www.medicalequipment-msl.com/htm/medical-device-news/India-is-about-to-approve-the-important-medical-legislation.html

India is about to approve the important medical legislation.

According to Indo Asian News Service (Indo Asian News Service) reported that in advance of a regulatory scheme,the Indian Ministry of Health agreed to examine new proposals put forward amendments to the Standing Committee.The Commission's proposal was shelved in December 2013,but now again been studied considering India's coalition cabinet. 
2013 proposed Drug and Cosmetic Act to amend laws governing medical devices do change.Under existing law(passed in 2007),medical devices and equipment are regarded as medicines blood analyzer.The new bill will separate standards and regulations for medical devices out,covering everything from clinical trials to the import and export of all matters.If you want the new regulations approved,coalition cabinet (including the Prime Minister and the Joint Ministerial) must first pass the bill,and get the council to make the final vote. 
Legal change is a big event in India's medical device industry,like Medtronic and Boston Scientific have targeted companies such as emerging markets,while the modern law will also promote long-term investment and major international partnerships. 
Ralph Ives,executive vice president of AdvaMed(Advanced Medical Technology Association of America )Global Strategy Analytics,said: "In the regulatory structure,the medical device is separated from the practice of pharmaceutical products out,indicating that demand for the medical device industry has been recognized by government departments,industries welcome this change and we believe that the face of India's growing health needs,the medical device industry Cheap EKG Machines will provide safe,effective,timely service,and the revised bill will enhance this service capabilities." 
The article comes from:http://www.medicalequipment-msl.com/htm/medical-device-news/India-is-about-to-approve-the-important-medical-legislation.html

Vital machines remain out of order at public hospitals

Data recently submitted to the Khyber-Pakhtunkhwa (K-P) Assembly revealed dysfunctional machinery at District Headquarters (DHQ) hospitals of Mansehra, Nowshera, Shangla, Kohat, Haripur, and Benazir Bhutto Shaheed Teaching 
The list of hospitals was submitted in response to Jamiat Ulema-e-Islam-Fazl lawmaker Mufti Syed Janan’s query about the state of medical machinery at district and tehsil headquarters hospitals. 
According to the documents, an X-ray machine worth Rs0.2 million, an ultrasound machine worth Rs0.18 million and two electrocardiography (ECG) machines(chemistry analyzer for sale) of Rs50,000 each are lying dysfunctional at Shah Abdullah Teaching Hospital, Mansehra. 
At DHQ Hospital Nowshera, four X-ray machines worth Rs4 million, an exercise tolerance test (ETT) machine worth Rs0.8 million and an ECG machine worth Rs0.4 million remain out of order. 
Similarly, six cardiac monitors, a ventilator, three large sterilisers, and dialysis, ultrasound and anesthesia machines are defective at DHQ Hospital Shangla. Moreover, physiotherapy and autoclave machines, a colposcope, generator, X-ray film dryer and section machine are lying unused due to a shortage of staff. 
 
The report further stated the surgical and orthopedic sections of DHQ Kohat Teaching Hospital’s operation theatre (OT) are not functional. Two autoclaves, one bone drill, a diathermy machine, an orthopedic OT table, a cystoscope, a generator, four laryngoscopes, an anesthesia machine, a ventilator, an oxygen concentrator and an image intensifier worth a total of Rs5 million are also out of order. 
Moreover, in the hospital’s ENT unit, two head lights, two bronchoscopes, two suction machines,hematology analyzerhemotology analyzer,two autoclaves and a microscope are non-functional. The total cost of all these machines is Rs2.8 million. A holter monitor, defibrillator and the ECG, EET and X-ray machines have been rusting away for several years as they are not in working condition. 
Several other essential machines in the dental unit, main store, laboratory and dialysis unit are lying dysfunctional at DHQ Kohat Teaching Hospital. 
The report also revealed 30 machines used for various purposes at DHQ Hospital Haripur are in need of repair. 
At the Benazir Bhutto Shaheed Teaching Hospital Abbottabad, X-ray, ultrasound and dialysis machines have not been in use for several years as they do not work. 
In response, Minister for Health Shaukat Yousafzai told lawmakers the provincial government was starting the overhaul of hospitals from scratch and will soon provide data for all hospitals of the province. He said the health department had no record of the total number of doctors in K-P. 
The government is streamlining health affairs of the province which will materialise in due time, claimed Yousafzai. 
The article comes from:http://www.medicalequipment-msl.com/htm/medical-device-news/hematology-analyzer-for-sale.html

Vital machines remain out of order at public hospitals

Data recently submitted to the Khyber-Pakhtunkhwa (K-P) Assembly revealed dysfunctional machinery at District Headquarters (DHQ) hospitals of Mansehra, Nowshera, Shangla, Kohat, Haripur, and Benazir Bhutto Shaheed Teaching 
The list of hospitals was submitted in response to Jamiat Ulema-e-Islam-Fazl lawmaker Mufti Syed Janan’s query about the state of medical machinery at district and tehsil headquarters hospitals. 
According to the documents, an X-ray machine worth Rs0.2 million, an ultrasound machine worth Rs0.18 million and two electrocardiography (ECG) machines(chemistry analyzer for sale) of Rs50,000 each are lying dysfunctional at Shah Abdullah Teaching Hospital, Mansehra. 
At DHQ Hospital Nowshera, four X-ray machines worth Rs4 million, an exercise tolerance test (ETT) machine worth Rs0.8 million and an ECG machine worth Rs0.4 million remain out of order. 
Similarly, six cardiac monitors, a ventilator, three large sterilisers, and dialysis, ultrasound and anesthesia machines are defective at DHQ Hospital Shangla. Moreover, physiotherapy and autoclave machines, a colposcope, generator, X-ray film dryer and section machine are lying unused due to a shortage of staff. 
 
The report further stated the surgical and orthopedic sections of DHQ Kohat Teaching Hospital’s operation theatre (OT) are not functional. Two autoclaves, one bone drill, a diathermy machine, an orthopedic OT table, a cystoscope, a generator, four laryngoscopes, an anesthesia machine, a ventilator, an oxygen concentrator and an image intensifier worth a total of Rs5 million are also out of order. 
Moreover, in the hospital’s ENT unit, two head lights, two bronchoscopes, two suction machines,hematology analyzerhemotology analyzer,two autoclaves and a microscope are non-functional. The total cost of all these machines is Rs2.8 million. A holter monitor, defibrillator and the ECG, EET and X-ray machines have been rusting away for several years as they are not in working condition. 
Several other essential machines in the dental unit, main store, laboratory and dialysis unit are lying dysfunctional at DHQ Kohat Teaching Hospital. 
The report also revealed 30 machines used for various purposes at DHQ Hospital Haripur are in need of repair. 
At the Benazir Bhutto Shaheed Teaching Hospital Abbottabad, X-ray, ultrasound and dialysis machines have not been in use for several years as they do not work. 
In response, Minister for Health Shaukat Yousafzai told lawmakers the provincial government was starting the overhaul of hospitals from scratch and will soon provide data for all hospitals of the province. He said the health department had no record of the total number of doctors in K-P. 
The government is streamlining health affairs of the province which will materialise in due time, claimed Yousafzai. 
The article comes from:http://www.medicalequipment-msl.com/htm/medical-device-news/hematology-analyzer-for-sale.html